HOW DOES THE COVID-19 Ab/Ag RAPID TESTS WORK?

The COVID-19 Ab test is a rapid serological test. It detects the presence of IgG and IgM antibodies to Covid-19 – not the virus. The test consists of two components, an IgG component, and an IgM component.

IgM positive result indicates current or recent infection with the SARS-CoV-2 virus. IgM antibodies are usually detected 3-5 days post symptom onset in symptomatic patients and around 7 days post- infection in asymptomatic patients.

IgG positive result indicates past exposure to SARS-CoV-2. IgG antibodies are usually produced 21 days post-infection and can be detected for months to years later. The duration of human immunity to SARS-CoV-2 remains to be determined.

IgM and IgG positive result indicate recent SARS-CoV-2 infection that occurred between one to two months prior to performed test.

Negative result does not preclude SARS-CoV-2 infection and should not be used as the sole basis for patient management decisions. Negative results must be combined with other clinical observations, patient history, and epidemiological information.

The COVID-19 Ag test is a rapid nasal swab test. It detects the presence of SARS-CoV-2 virus.

Negative results, from patients with symptom onset beyond five days, should be treated as presumptive and confirmation with a molecular assay, if necessary for patient management, may be performed.

Positive test results do not rule out co-infections with other pathogens and do not differentiate between SARS-CoV and SARS-CoV-2.

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